Renal transplant patient with polyoma virus bladder infection and subsequent polyoma virus nephropathy

David B. Weinreb, Garrett T. Desman, David E. Burstein, Steven H. Dikman, Edward M. Johnson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Polyoma virus nephropathy (PVN) is a significant cause of renal allograft dysfunction in transplant patients. A 58-year-old male received a cadaveric renal transplant and 12 weeks later presented with fever, diarrhea, and dysuria. He was diagnosed with a polyoma virus infection of the bladder by a transurethral bladder biopsy. One year post-transplant, he presented with renal allograft dysfunction and was diagnosed by biopsy with PVN of the non-native kidney. The diagnosis of a polyoma virus infection was confirmed by immunoreactivity to the polyoma T-antigen. We suggest that polyoma virus infection of the bladder be included in the differential diagnosis of urinary dysfunction in post-transplant patients, as such infections might be an under-recognized comorbidity in individuals with PVN.

Original languageEnglish
Pages (from-to)439-441
Number of pages3
JournalInternational Journal of Urology
Volume13
Issue number4
DOIs
StatePublished - Apr 2006

Keywords

  • Bladder
  • Polyoma virus
  • Renal transplant

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