Relevance of Brain 18F-FDG PET Imaging in Probable Seronegative Encephalitis With Catatonia: A Case Report

Michaël Guetta; Aurélie Kas; Aveline Aouidad; Marine Soret; Yves Allenbach; Manon Bordonné; Alice Oppetit; Marie Raffin; Dimitri Psimaras; David Cohen; Angèle Consoli

doi:10.3389/fpsyt.2021.685711

Relevance of Brain ¹⁸F-FDG PET Imaging in Probable Seronegative Encephalitis With Catatonia: A Case Report

Michaël Guetta, Aurélie Kas, Aveline Aouidad, Marine Soret, Yves Allenbach, Manon Bordonné, Alice Oppetit, Marie Raffin, Dimitri Psimaras, David Cohen, Angèle Consoli

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Autoimmune encephalitis (AIE) is a rare, severe, and rapidly progressive encephalopathy, and its diagnosis is challenging, especially in adolescent populations when the presentation is mainly psychiatric. Currently, cerebral 18-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG-PET) imaging is not included in the diagnosis algorithm. We describe a 16-year-old patient with probable seronegative encephalitis with catatonia for which several cerebral PET scans were relevant and helpful for diagnosis, treatment decision making, and follow-up monitoring. The patient recovered after 2 years of treatment with etiologic treatment of AIE and treatment of catatonia. This case suggests a more systematic assessment of the clinical relevance of ¹⁸F-FDG-PET imaging in probable seronegative AIE.

Original language	English
Article number	685711
Journal	Frontiers in Psychiatry
Volume	12
DOIs	https://doi.org/10.3389/fpsyt.2021.685711
State	Published - 9 Jun 2021
Externally published	Yes

Keywords

abnormal movement
adolescence
catatonia
cerebral PET/CT
encephalitis

Access to Document

10.3389/fpsyt.2021.685711

Cite this

@article{38f642b4b4ef416a8fe2441bb1478c1a,

title = "Relevance of Brain 18F-FDG PET Imaging in Probable Seronegative Encephalitis With Catatonia: A Case Report",

abstract = "Autoimmune encephalitis (AIE) is a rare, severe, and rapidly progressive encephalopathy, and its diagnosis is challenging, especially in adolescent populations when the presentation is mainly psychiatric. Currently, cerebral 18-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) imaging is not included in the diagnosis algorithm. We describe a 16-year-old patient with probable seronegative encephalitis with catatonia for which several cerebral PET scans were relevant and helpful for diagnosis, treatment decision making, and follow-up monitoring. The patient recovered after 2 years of treatment with etiologic treatment of AIE and treatment of catatonia. This case suggests a more systematic assessment of the clinical relevance of 18F-FDG-PET imaging in probable seronegative AIE.",

keywords = "abnormal movement, adolescence, catatonia, cerebral PET/CT, encephalitis",

author = "Micha{\"e}l Guetta and Aur{\'e}lie Kas and Aveline Aouidad and Marine Soret and Yves Allenbach and Manon Bordonn{\'e} and Alice Oppetit and Marie Raffin and Dimitri Psimaras and David Cohen and Ang{\`e}le Consoli",

note = "Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2021 Guetta, Kas, Aouidad, Soret, Allenbach, Bordonn{\'e}, Oppetit, Raffin, Psimaras, Cohen and Consoli.",

year = "2021",

month = jun,

day = "9",

doi = "10.3389/fpsyt.2021.685711",

language = "English",

volume = "12",

journal = "Frontiers in Psychiatry",

issn = "1664-0640",

publisher = "Frontiers Media S.A.",

}

TY - JOUR

T1 - Relevance of Brain 18F-FDG PET Imaging in Probable Seronegative Encephalitis With Catatonia

T2 - A Case Report

AU - Guetta, Michaël

AU - Kas, Aurélie

AU - Aouidad, Aveline

AU - Soret, Marine

AU - Allenbach, Yves

AU - Bordonné, Manon

AU - Oppetit, Alice

AU - Raffin, Marie

AU - Psimaras, Dimitri

AU - Cohen, David

AU - Consoli, Angèle

PY - 2021/6/9

Y1 - 2021/6/9

N2 - Autoimmune encephalitis (AIE) is a rare, severe, and rapidly progressive encephalopathy, and its diagnosis is challenging, especially in adolescent populations when the presentation is mainly psychiatric. Currently, cerebral 18-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) imaging is not included in the diagnosis algorithm. We describe a 16-year-old patient with probable seronegative encephalitis with catatonia for which several cerebral PET scans were relevant and helpful for diagnosis, treatment decision making, and follow-up monitoring. The patient recovered after 2 years of treatment with etiologic treatment of AIE and treatment of catatonia. This case suggests a more systematic assessment of the clinical relevance of 18F-FDG-PET imaging in probable seronegative AIE.

AB - Autoimmune encephalitis (AIE) is a rare, severe, and rapidly progressive encephalopathy, and its diagnosis is challenging, especially in adolescent populations when the presentation is mainly psychiatric. Currently, cerebral 18-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) imaging is not included in the diagnosis algorithm. We describe a 16-year-old patient with probable seronegative encephalitis with catatonia for which several cerebral PET scans were relevant and helpful for diagnosis, treatment decision making, and follow-up monitoring. The patient recovered after 2 years of treatment with etiologic treatment of AIE and treatment of catatonia. This case suggests a more systematic assessment of the clinical relevance of 18F-FDG-PET imaging in probable seronegative AIE.

KW - abnormal movement

KW - adolescence

KW - catatonia

KW - cerebral PET/CT

KW - encephalitis

UR - http://www.scopus.com/inward/record.url?scp=85108356284&partnerID=8YFLogxK

U2 - 10.3389/fpsyt.2021.685711

DO - 10.3389/fpsyt.2021.685711

M3 - Article

AN - SCOPUS:85108356284

SN - 1664-0640

VL - 12

JO - Frontiers in Psychiatry

JF - Frontiers in Psychiatry

M1 - 685711