Relationship of Rat Anaphylaxis to Time of Challenge

Raul C. Schiavi, Thomas J. Luparello, Catherine H. Fales, Marvin Stein

Research output: Contribution to journalArticlepeer-review


The present study compared the dose-mortality curves of sensitized rats kept under conditions standardized for periodicity analysis and challenged with an antigen at 4-hour intervals during a 24-hour period. There were no differences in susceptibility to lethal anaphylaxis in relation to time of challenge. The findings are discussed in terms of circadian variations in pituitary-adrenocortical function.

Original languageEnglish
Pages (from-to)688-690
Number of pages3
JournalExperimental Biology and Medicine
Issue number3
StatePublished - Jul 1965
Externally publishedYes


Dive into the research topics of 'Relationship of Rat Anaphylaxis to Time of Challenge'. Together they form a unique fingerprint.

Cite this