Relationship of Rat Anaphylaxis to Time of Challenge

Raul C. Schiavi; Thomas J. Luparello; Catherine H. Fales; Marvin Stein

doi:10.3181/00379727-119-30272

Relationship of Rat Anaphylaxis to Time of Challenge

Raul C. Schiavi, Thomas J. Luparello, Catherine H. Fales, Marvin Stein

Research output: Contribution to journal › Article › peer-review

Abstract

The present study compared the dose-mortality curves of sensitized rats kept under conditions standardized for periodicity analysis and challenged with an antigen at 4-hour intervals during a 24-hour period. There were no differences in susceptibility to lethal anaphylaxis in relation to time of challenge. The findings are discussed in terms of circadian variations in pituitary-adrenocortical function.

Original language	English
Pages (from-to)	688-690
Number of pages	3
Journal	Experimental Biology and Medicine
Volume	119
Issue number	3
DOIs	https://doi.org/10.3181/00379727-119-30272
State	Published - Jul 1965
Externally published	Yes

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title = "Relationship of Rat Anaphylaxis to Time of Challenge",

abstract = "The present study compared the dose-mortality curves of sensitized rats kept under conditions standardized for periodicity analysis and challenged with an antigen at 4-hour intervals during a 24-hour period. There were no differences in susceptibility to lethal anaphylaxis in relation to time of challenge. The findings are discussed in terms of circadian variations in pituitary-adrenocortical function.",

author = "Schiavi, {Raul C.} and Luparello, {Thomas J.} and Fales, {Catherine H.} and Marvin Stein",

year = "1965",

month = jul,

doi = "10.3181/00379727-119-30272",

language = "English",

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AU - Schiavi, Raul C.

AU - Luparello, Thomas J.

AU - Fales, Catherine H.

AU - Stein, Marvin

PY - 1965/7

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N2 - The present study compared the dose-mortality curves of sensitized rats kept under conditions standardized for periodicity analysis and challenged with an antigen at 4-hour intervals during a 24-hour period. There were no differences in susceptibility to lethal anaphylaxis in relation to time of challenge. The findings are discussed in terms of circadian variations in pituitary-adrenocortical function.

AB - The present study compared the dose-mortality curves of sensitized rats kept under conditions standardized for periodicity analysis and challenged with an antigen at 4-hour intervals during a 24-hour period. There were no differences in susceptibility to lethal anaphylaxis in relation to time of challenge. The findings are discussed in terms of circadian variations in pituitary-adrenocortical function.

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DO - 10.3181/00379727-119-30272

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SP - 688

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JO - Experimental Biology and Medicine

JF - Experimental Biology and Medicine

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Relationship of Rat Anaphylaxis to Time of Challenge

Abstract

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