Regulation of pro-σK activation: a key checkpoint in Bacillus subtilis sporulation

Gaohui Sun, Moua Yang, Longguang Jiang, Mingdong Huang

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

The Gram-positive bacterium Bacillus subtilis initiates the sporulation process under conditions of nutrient limitation. Here, we review related work in this field, focusing on the protein processing of the pro-σK activation. The purpose of this review is to illustrate the mechanism of pro-σK activation and provide structural insights into the regulation of spore production. Sporulation is not only important in basic science but also provides mechanistic insight for bacterial control in applications in, e.g., food industry.

Original languageEnglish
Pages (from-to)2366-2373
Number of pages8
JournalEnvironmental Microbiology
Volume23
Issue number5
DOIs
StatePublished - May 2021
Externally publishedYes

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