Regulation of immune reactivity by intercellular transfer

Maxime Dhainaut, Muriel Moser

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

It was recently proposed that T lymphocytes, which closely interact with APCs, can extract surface molecules from the presenting cells when they dissociate. These observations question the classical view of discrete interactions between phenotypically defined cell populations. In this review, we summarize some reports suggesting that membrane exchange at the immune synapse can be a vector for intercellular communication and envisage some consequences on the biology of T cells.

Original languageEnglish
Article numberArticle 112
JournalFrontiers in Immunology
Volume5
Issue numberMAR
DOIs
StatePublished - 2014
Externally publishedYes

Keywords

  • Costimulation
  • Immune regulation
  • T cell activation
  • T/APC interaction
  • Trogocytosis

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