Regulation of ADAMTS Proteases

Keyphrases

• ADAMTS Proteases 100%
• ADAMTS 30%
• Extracellular Matrix 20%
• Protease Activity 20%
• Extracellular Matrix Protein 1 (ECM1) 20%
• ADAMTS5 20%
• ADAMTS-4 20%
• Thrombospondin-1 (TSP-1) 10%
• Disintegrin 10%
• Metalloprotease 10%
• Organ System 10%
• Gene Expression 10%
• Pharmacological Approaches 10%
• Post-translational Modification 10%
• Clinical Indications 10%
• Sequence Homology 10%
• Specific Inhibitor 10%
• Total Joint Arthroplasty 10%
• Homeostasis 10%
• Metalloproteinases 10%
• Proteolytic Activity 10%
• Tissue Destruction 10%
• Arthritis 10%
• Aggrecan 10%
• Major Contributor 10%
• Beneficial Functions 10%
• Joint Damage 10%
• Furin 10%
• Major Constituents 10%
• Physiological Adaptation 10%
• Hyalectan 10%
• Cartilage Erosion 10%
• Catalytically Active Sites 10%
• Post-translational 10%
• Aggrecanase 10%
• Cartilage 10%
• Endogenous Inhibitor 10%
• Substrate Cleavage 10%
• Substrate Spectrum 10%
• I-motif 10%

Biochemistry, Genetics and Molecular Biology

• Protease 100%
• ADAMTS 100%
• Metalloproteinase 15%
• ADAMTS5 15%
• Extracellular Matrix Proteins 15%
• Scleroprotein 15%
• ADAMTS4 15%
• Homeostasis 7%
• Active Site 7%
• Posttranslational Modification 7%
• Gene Expression 7%
• Protein Catabolism 7%
• Sequence Homology 7%
• Aggrecan 7%
• Metalloendopeptidase 7%
• Thrombospondin 7%
• Disintegrin 7%
• Adaptation 7%
• Furin 7%
• Aggrecanase 7%