Reflectance Confocal Microscopy for Skin Cancer Margins: How it Works

Michael C. Cameron, Anthony M. Rossi

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Since its first application to human skin imaging in 1995, confocal microscopy has continued to improve as both a noninvasive, in vivo imaging technique for intact skin and an efficient and cost-effective ex vivo imaging approach for excised skin. The purpose of this article is to present the principles behind confocal microscopy imaging of skin, provide a frame of reference regarding where the technology currently stands in its development towards widespread clinical practice, and elucidate how confocal microscopy can be used for preoperative and intraoperative delineation of skin cancer margins.

Original languageEnglish
Pages (from-to)172-178
Number of pages7
JournalCurrent Dermatology Reports
Issue number3
StatePublished - 1 Sep 2016
Externally publishedYes


  • Confocal microscopy
  • Dermatologic surgery
  • Fluorescence confocal microscopy
  • Lentigo maligna
  • Margin control
  • Melanoma
  • Mohs micrographic surgery
  • Non-melanoma skin cancer
  • Reflectance confocal microscopy
  • Skin cancer
  • Skin cancer margins


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