Red Blood Cells from Stem Cells

Anna Rita Migliaccio, Carolyn Whitsett, Giovanni Migliaccio

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations
Original languageEnglish
Title of host publicationChemistry and Biochemistry of Oxygen Therapeutics
Subtitle of host publicationFrom Transfusion to Artificial Blood
PublisherJohn Wiley and Sons
Number of pages15
ISBN (Print)9780470686683
StatePublished - 4 Jul 2011


  • Alternative sources of stem cells - properties of ex vivo-generated erythroid cells
  • Biomarkers, monitoring EB expansion - in production
  • Hypothetical ex vivo red cell production process anatomy
  • Model for mechanism of action of GR and ESR - on erythroid maturation, transcription factor GATA1
  • Red blood cells - from stem cells
  • Red cells, cellular elements of blood - oxygen delivery, tissues of body
  • Safety concerns, for cell therapy - product exposure, xenogeneic substances
  • Specific growth factors (GFs) - pluripotent hemopoietic stem cells (HSCs), and EPCs
  • Stem-cell sources for ex vivo generation - of erythroid cells, as transfusion product
  • ex vivo-expanded EBs for alloimmunized patients - alloimmunization, in multitransfused patients

Cite this