Recognition of influenza A virus nucleoprotein by an H-2-restricted cytotoxic T-cell clone

A. R.M. Townsend, J. J. Skehel, P. M. Taylor, P. Palese

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Cytotoxic T-cell clones raised against X-31 (H3N2) influenza virus in C57BL/6 mice can be directed against an influenza A virus subtype specific determinant (1). A representative T-cell clone (A3.1) has been used in combination with a set of genetically typed recombinant viruses, to show that the A/PR/8/34 nucleoprotein can be responsible for cytotoxic T-lymphocyte recognition of infected target cells.

Original languageEnglish
Pages (from-to)456-459
Number of pages4
JournalVirology
Volume133
Issue number2
DOIs
StatePublished - Mar 1984

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