Reclassifying pseudopolyps in inflammatory bowel disease: Histologic and endoscopic description in the new era of mucosal healing

Mona Rezapour; Maria Alejandra Quintero; Nidah S. Khakoo; Daniel A. Sussman; Jodie A. Barkin; Jennifer Clarke; Tanya Varma; Amar R. Deshpande; David H. Kerman; Oriana Damas; Maria T. Abreu

doi:10.1093/crocol/otz033

Reclassifying pseudopolyps in inflammatory bowel disease: Histologic and endoscopic description in the new era of mucosal healing

Mona Rezapour, Maria Alejandra Quintero, Nidah S. Khakoo, Daniel A. Sussman, Jodie A. Barkin, Jennifer Clarke, Tanya Varma, Amar R. Deshpande, David H. Kerman, Oriana Damas, Maria T. Abreu

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Introduction: In this study, we identify the frequency of pseudopolyps (PPs) with normal histology and their association to surrounding tissue. Methods: Patients were enrolled in a study identifying endoscopic characteristics of PPs (n = 29) or were collected as part of our IBD biobank (n = 16). Statistical analysis included Stata v.15.0. chi-square and Student t-test. Results: A total of 45 patients with 117 PP biopsies were identified. More patients with healed PP were in endoscopic remission compared with those with inflammatory PP (82.6% vs 17.4%, respectively). Conclusion: This is the first study to find mucosal healing of PPs and its association with deep remission.

Original language	English
Journal	Crohn's and Colitis 360
Volume	1
Issue number	3
DOIs	https://doi.org/10.1093/crocol/otz033
State	Published - 1 Oct 2019
Externally published	Yes

Keywords

Healed pseudopolyps
Inflammatory bowel disease
Inflammatory pseudopolyps

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10.1093/crocol/otz033

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title = "Reclassifying pseudopolyps in inflammatory bowel disease: Histologic and endoscopic description in the new era of mucosal healing",

abstract = "Introduction: In this study, we identify the frequency of pseudopolyps (PPs) with normal histology and their association to surrounding tissue. Methods: Patients were enrolled in a study identifying endoscopic characteristics of PPs (n = 29) or were collected as part of our IBD biobank (n = 16). Statistical analysis included Stata v.15.0. chi-square and Student t-test. Results: A total of 45 patients with 117 PP biopsies were identified. More patients with healed PP were in endoscopic remission compared with those with inflammatory PP (82.6% vs 17.4%, respectively). Conclusion: This is the first study to find mucosal healing of PPs and its association with deep remission.",

keywords = "Healed pseudopolyps, Inflammatory bowel disease, Inflammatory pseudopolyps",

author = "Mona Rezapour and Quintero, {Maria Alejandra} and Khakoo, {Nidah S.} and Sussman, {Daniel A.} and Barkin, {Jodie A.} and Jennifer Clarke and Tanya Varma and Deshpande, {Amar R.} and Kerman, {David H.} and Oriana Damas and Abreu, {Maria T.}",

note = "Publisher Copyright: {\textcopyright} 2019 Crohn's & Colitis Foundation. Published by Oxford University Press on behalf of Crohn's & Colitis Foundation.",

year = "2019",

month = oct,

day = "1",

doi = "10.1093/crocol/otz033",

language = "English",

volume = "1",

journal = "Crohn's and Colitis 360",

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TY - JOUR

T1 - Reclassifying pseudopolyps in inflammatory bowel disease

T2 - Histologic and endoscopic description in the new era of mucosal healing

AU - Rezapour, Mona

AU - Quintero, Maria Alejandra

AU - Khakoo, Nidah S.

AU - Sussman, Daniel A.

AU - Barkin, Jodie A.

AU - Clarke, Jennifer

AU - Varma, Tanya

AU - Deshpande, Amar R.

AU - Kerman, David H.

AU - Damas, Oriana

AU - Abreu, Maria T.

PY - 2019/10/1

Y1 - 2019/10/1

N2 - Introduction: In this study, we identify the frequency of pseudopolyps (PPs) with normal histology and their association to surrounding tissue. Methods: Patients were enrolled in a study identifying endoscopic characteristics of PPs (n = 29) or were collected as part of our IBD biobank (n = 16). Statistical analysis included Stata v.15.0. chi-square and Student t-test. Results: A total of 45 patients with 117 PP biopsies were identified. More patients with healed PP were in endoscopic remission compared with those with inflammatory PP (82.6% vs 17.4%, respectively). Conclusion: This is the first study to find mucosal healing of PPs and its association with deep remission.

AB - Introduction: In this study, we identify the frequency of pseudopolyps (PPs) with normal histology and their association to surrounding tissue. Methods: Patients were enrolled in a study identifying endoscopic characteristics of PPs (n = 29) or were collected as part of our IBD biobank (n = 16). Statistical analysis included Stata v.15.0. chi-square and Student t-test. Results: A total of 45 patients with 117 PP biopsies were identified. More patients with healed PP were in endoscopic remission compared with those with inflammatory PP (82.6% vs 17.4%, respectively). Conclusion: This is the first study to find mucosal healing of PPs and its association with deep remission.

KW - Healed pseudopolyps

KW - Inflammatory bowel disease

KW - Inflammatory pseudopolyps

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U2 - 10.1093/crocol/otz033

DO - 10.1093/crocol/otz033

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VL - 1

JO - Crohn's and Colitis 360

JF - Crohn's and Colitis 360

IS - 3

ER -

Reclassifying pseudopolyps in inflammatory bowel disease: Histologic and endoscopic description in the new era of mucosal healing

Abstract

Keywords

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