Recent trends in epidemiology of dyslipidemias in India

Rajeev Gupta, Ravinder S. Rao, Anoop Misra, Samin K. Sharma

Research output: Contribution to journalReview articlepeer-review

75 Scopus citations

Abstract

Dyslipidemia is the most important atherosclerotic risk factor. Review of population based studies in India shows increasing mean total cholesterol levels. Recent studies have reported that high cholesterol is present in 25–30% of urban and 15–20% rural subjects. This prevalence is lower than high-income countries. The most common dyslipidemia in India are borderline high LDL cholesterol, low HDL cholesterol and high triglycerides. Studies have reported that over a 20-year period total cholesterol, LDL cholesterol and triglyceride levels have increased among urban populations. Case-control studies have reported that there is significant association of coronary events with raised apolipoproteinB, total cholesterol, LDL cholesterol and non-HDL cholesterol and inverse association with high apolipoproteinA and HDL cholesterol. Prevalence of suspected familial hypercholesterolemia in urban subjects varies from 1:125 to 1:450. Only limited studies exist regarding lipid abnormalities in children. There is low awareness, treatment and control of hypercholesterolemia in India.

Original languageEnglish
Pages (from-to)382-392
Number of pages11
JournalIndian Heart Journal
Volume69
Issue number3
DOIs
StatePublished - May 2017

Keywords

  • Cardiovascular disease
  • Cholesterol
  • Coronary heart disease
  • Hypercholesterolemia
  • Lipids
  • Lower middle income countries

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