Abstract
The advent of single-cell sequencing has been revolutionary to the field of cancer genomics. Perfectly suited to capture cancer's heterogeneous nature, single-cell analyses provide information bulk sequencing could never hope to uncover. Many mechanisms of cancer have yet to be fully understood, and single-cell approaches are showing promise in their abilities to uncover these mysteries. Here we focus on the most recent single-cell methods for cancer genomics, and how they are not only providing insights into the inner workings of cancer, but are also transforming individualized therapy and non-invasive monitoring and diagnosis.
| Original language | English |
|---|---|
| Pages (from-to) | 22-32 |
| Number of pages | 11 |
| Journal | Current Opinion in Genetics and Development |
| Volume | 42 |
| DOIs | |
| State | Published - 1 Feb 2017 |
| Externally published | Yes |
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