Recent Advances in Stent Technology: Do They Reduce Cardiovascular Events?

Allen J. Weiss, Marta Lorente-Ros, Ashish Correa, Nitin Barman, Jacqueline E. Tamis-Holland

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Purpose of Review: Drug-eluting stents are used in nearly all cases of percutaneous coronary revascularization and have been shown to be superior to balloon angioplasty or bare metal stents. The designs of these stents are continually evolving to maximize efficacy and safety. Recent Findings: This review outlines the important components of a drug-eluting stent and highlights the changes in stent design that have led to the optimization of clinical outcomes. Most stents used in contemporary times are thin strut, durable polymer drug-eluting stents (DES) that elute either everolimus or zotarolimus. Newer DES designs incorporating bioresorbable polymers or ultrathin struts have shown encouraging safety and efficacy profiles. Summary: DES are essential for the management of patients with obstructive coronary artery disease and are used in most coronary interventions. Changes in stent designs over the past 30 years reflect the ongoing need to address the limitations of earlier stents aimed to improve patient outcomes.

Original languageEnglish
Pages (from-to)731-744
Number of pages14
JournalCurrent Atherosclerosis Reports
Volume24
Issue number9
DOIs
StatePublished - Sep 2022

Keywords

  • Bioresorbable polymer
  • Drug-eluting stent
  • Drug-eluting stent architecture
  • Drug-eluting stent technology
  • Percutaneous coronary intervention
  • Ultrathin struts

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