TY - JOUR
T1 - Recent Advances in Stent Technology
T2 - Do They Reduce Cardiovascular Events?
AU - Weiss, Allen J.
AU - Lorente-Ros, Marta
AU - Correa, Ashish
AU - Barman, Nitin
AU - Tamis-Holland, Jacqueline E.
N1 - Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2022/9
Y1 - 2022/9
N2 - Purpose of Review: Drug-eluting stents are used in nearly all cases of percutaneous coronary revascularization and have been shown to be superior to balloon angioplasty or bare metal stents. The designs of these stents are continually evolving to maximize efficacy and safety. Recent Findings: This review outlines the important components of a drug-eluting stent and highlights the changes in stent design that have led to the optimization of clinical outcomes. Most stents used in contemporary times are thin strut, durable polymer drug-eluting stents (DES) that elute either everolimus or zotarolimus. Newer DES designs incorporating bioresorbable polymers or ultrathin struts have shown encouraging safety and efficacy profiles. Summary: DES are essential for the management of patients with obstructive coronary artery disease and are used in most coronary interventions. Changes in stent designs over the past 30 years reflect the ongoing need to address the limitations of earlier stents aimed to improve patient outcomes.
AB - Purpose of Review: Drug-eluting stents are used in nearly all cases of percutaneous coronary revascularization and have been shown to be superior to balloon angioplasty or bare metal stents. The designs of these stents are continually evolving to maximize efficacy and safety. Recent Findings: This review outlines the important components of a drug-eluting stent and highlights the changes in stent design that have led to the optimization of clinical outcomes. Most stents used in contemporary times are thin strut, durable polymer drug-eluting stents (DES) that elute either everolimus or zotarolimus. Newer DES designs incorporating bioresorbable polymers or ultrathin struts have shown encouraging safety and efficacy profiles. Summary: DES are essential for the management of patients with obstructive coronary artery disease and are used in most coronary interventions. Changes in stent designs over the past 30 years reflect the ongoing need to address the limitations of earlier stents aimed to improve patient outcomes.
KW - Bioresorbable polymer
KW - Drug-eluting stent
KW - Drug-eluting stent architecture
KW - Drug-eluting stent technology
KW - Percutaneous coronary intervention
KW - Ultrathin struts
UR - http://www.scopus.com/inward/record.url?scp=85134302320&partnerID=8YFLogxK
U2 - 10.1007/s11883-022-01049-z
DO - 10.1007/s11883-022-01049-z
M3 - Review article
C2 - 35821187
AN - SCOPUS:85134302320
SN - 1523-3804
VL - 24
SP - 731
EP - 744
JO - Current Atherosclerosis Reports
JF - Current Atherosclerosis Reports
IS - 9
ER -