Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives

Nitesh K. Nandwana; Om P.S. Patel; Manish K. Mehra; Anil Kumar; Joseph M. Salvino

doi:10.3390/molecules29102353

Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives

Nitesh K. Nandwana
, Om P.S. Patel
, Manish K. Mehra
, Anil Kumar
, Joseph M. Salvino

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.

Original language	English
Article number	2353
Journal	Molecules
Volume	29
Issue number	10
DOIs	https://doi.org/10.3390/molecules29102353
State	Published - May 2024
Externally published	Yes

Keywords

C-H activation
cascade reactions
intramolecular dehydrative/dehydrogenative cyclizations
quinazoline heterocycles
transition metal-catalyzed synthesis

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10.3390/molecules29102353

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title = "Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives",

abstract = "Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.",

keywords = "C-H activation, cascade reactions, intramolecular dehydrative/dehydrogenative cyclizations, quinazoline heterocycles, transition metal-catalyzed synthesis",

author = "Nandwana, \{Nitesh K.\} and Patel, \{Om P.S.\} and Mehra, \{Manish K.\} and Anil Kumar and Salvino, \{Joseph M.\}",

note = "Publisher Copyright: {\textcopyright} 2024 by the authors.",

year = "2024",

month = may,

doi = "10.3390/molecules29102353",

language = "English",

volume = "29",

journal = "Molecules",

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T1 - Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives

AU - Nandwana, Nitesh K.

AU - Patel, Om P.S.

AU - Mehra, Manish K.

AU - Kumar, Anil

AU - Salvino, Joseph M.

PY - 2024/5

Y1 - 2024/5

N2 - Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.

AB - Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.

KW - C-H activation

KW - cascade reactions

KW - intramolecular dehydrative/dehydrogenative cyclizations

KW - quinazoline heterocycles

KW - transition metal-catalyzed synthesis

UR - https://www.scopus.com/pages/publications/85194173750

U2 - 10.3390/molecules29102353

DO - 10.3390/molecules29102353

M3 - Review article

C2 - 38792215

AN - SCOPUS:85194173750

SN - 1420-3049

VL - 29

JO - Molecules

JF - Molecules

IS - 10

M1 - 2353

ER -

Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives

Abstract

Keywords

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