Abstract
The measurement of the electrical impedance of living cells over a wide frequency range presents many technical difficulties. Besides the measurement problems for cell suspensions, which include low sensitivity in detection and the geometry/orientation, there is the problem of maintaining the cells or tissue in a living condition. In order to increase sensitivity for the measurement a method was developed whereby the cells are forced gently into the cylindrical pores of a thin insulating film, creating a pseudo-epithelium. The cells are maintained in a physiologic environment during the measurement. The results of these high-resolution cell membrane impedance measurements lend support to the hypothesis that the observable high-frequency capacitance is closely related to the membrane bilayer structure.
| Original language | English |
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| Pages | 518-521 |
| Number of pages | 4 |
| State | Published - 1987 |