Readmissions after Guillain-Barre Syndrome: Nationally Representative Data

Mallory Roberts, Peter Jin, Susan Shin, Mandip Dhamoon

Research output: Contribution to journalArticlepeer-review


Objectives:We aimed to obtain nationally representative data on hospital readmission rates after Guillain-Barre syndrome (GBS).Methods:International Classification of Disease, Ninth Revision codes from the 2013 National Readmissions Database identified adult GBS admissions, comorbidities, and readmission diagnoses. Logistic regression estimated odds ratios (ORs) for readmission.Results:Of 2109 GBS admissions identified, 20.8% were readmitted within 1 year and 12.2% within 30 days. Age did not predict readmission. Plasmapheresis use showed a nonsignificant trend toward readmission versus intravenous immunoglobulin use [OR 1.43, 95% confidence interval (CI) 1.00-2.051, P = 0.050]. Respiratory failure (OR 1.70, 95% CI 1.23-2.35, P = 0.0014), heart failure (OR 2.14, 95% CI 1.25-3.66, P = 0.0057), and renal failure (OR 2.00, 95% CI 1.20-3.32, P = 0.0078) predicted readmission. Top readmission diagnoses included GBS or chronic inflammatory demyelinating polyneuropathy (42.0%) and sepsis (3.5%).Conclusions:One-fifth of GBS patients were readmitted within 1 year. Comorbid illnesses and respiratory complications increased a readmission risk but age did not.

Original languageEnglish
Pages (from-to)183-191
Number of pages9
JournalJournal of Clinical Neuromuscular Disease
Issue number4
StatePublished - 1 Jun 2021


  • Guillain-Barre syndrome
  • complications
  • outcomes
  • readmission


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