Abstract
Type 2 diabetes mellitus being one of the most prevalent diseases in the world has led to a variety of research using animal models. This review focuses on various rat models to study the effect that surgical procedures have on type 2 diabetes mellitus and obesity. Rat models can be classified as Obese Diabetic, Non-Obese Diabetic, Obese Non-Diabetic, and Non-Obese Non-Diabetic. Here, we have discussed the particular characteristics of each rat so that it can provide the appropriate model to study different pathological processes involve in type 2 Diabetes and obesity.
| Original language | English |
|---|---|
| Pages (from-to) | 655-660 |
| Number of pages | 6 |
| Journal | Obesity Surgery |
| Volume | 19 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2009 |
Keywords
- Bariatric surgery
- Hyperglycemia
- Insulin resistance
- Obesity
- Rat models
- Spontaneously hypertensive rat/National Institute of Health corpulent (SHR/N-cp)
- Type 2 diabetes mellitus
- Weight loss
- Zucker diabetic fatty (ZDF)