RASopathy mutations open new insights into the mechanism of BRAF activation

Arvin C. Dar, Donita C. Brady

Research output: Contribution to journalComment/debate

1 Scopus citations

Abstract

Spencer-Smith et al. (2022)1 investigate multiple functions of the BRAF cysteine-rich domain (CRD), finding distinct classes of RASopathy-associated BRAF mutations and unique features among RAF paralogs that may contribute to the spectrum of mutations observed in disease.

Original languageEnglish
Pages (from-to)4192-4193
Number of pages2
JournalMolecular Cell
Volume82
Issue number22
DOIs
StatePublished - 17 Nov 2022

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