Radiosynthesis of the fluorinated sucrose analogue, 1'-[ ¹⁸F]fluoro-1'-deoxysucrose

Keyphrases

• Acetate 100%
• Fluoro 100%
• Radiosynthesis 100%
• Fluorinated 100%
• Triflate 100%
• Radiofluorination 100%
• Carbohydrates 50%
• Regioselectivity 50%
• Hydroxyl Group 50%
• Acyl 50%
• Disaccharides 50%
• Substrate Specificity 50%
• Protection Strategy 50%
• Deacetylation 50%
• HPLC Purification 50%
• Processing Enzymes 50%
• 18F-labeled 50%
• Base Hydrolysis 50%
• Synthesis Time 50%
• 18F-fluoride 50%
• Enzymatic Approach 50%
• Regiospecific 50%
• Trifluoromethanesulfonyl 50%
• Esterase Enzyme 50%
• Sucrose Stearate 50%

Chemistry

• Sucrose 100%
• Triflate 40%
• Acetate 40%
• Hydroxyl Group 20%
• Disaccharide 20%
• Deacetylation 20%
• Base 20%
• Substrate Specificity 20%
• High Performance Liquid Chromatography 20%
• Enzymatic Hydrolysis 20%
• Carbohydrates 20%
• Hydrolysis 20%
• Fluoride 20%