Abstract
Fasting human plasma immunoreactive leu-enkephalin (ir-leu-enkephalin) measured by radioimmunoassay averages 54±10 pg/ml. The method depends on acidification of plasma to protect against destruction of the peptide, adsorption to XAD-2 resin, extraction from the resin by aqueous methanol and concentration by evaporation. Plasma enkephalin in the dog increased from 13 to 56 pg/ml following insulin-induced hypoglycemia.
Original language | English |
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Pages (from-to) | 367-369 |
Number of pages | 3 |
Journal | Journal of Clinical Endocrinology and Metabolism |
Volume | 52 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1981 |
Externally published | Yes |