Radiation Dose-Volume Effects for Liver SBRT

Moyed Miften; Yevgeniy Vinogradskiy; Vitali Moiseenko; Jimm Grimm; Ellen Yorke; Andrew Jackson; Wolfgang A. Tomé; Randall K. Ten Haken; Nitin Ohri; Alejandra Méndez Romero; Karyn A. Goodman; Lawrence B. Marks; Brian Kavanagh; Laura A. Dawson

doi:10.1016/j.ijrobp.2017.12.290

Radiation Dose-Volume Effects for Liver SBRT

Moyed Miften
, Yevgeniy Vinogradskiy
, Vitali Moiseenko
, Jimm Grimm
, Ellen Yorke
, Andrew Jackson
, Wolfgang A. Tomé
, Randall K. Ten Haken
, Nitin Ohri
, Alejandra Méndez Romero
, Karyn A. Goodman
, Lawrence B. Marks
, Brian Kavanagh
, Laura A. Dawson

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

Abstract

Stereotactic body radiation therapy (SBRT) has emerged as an effective, noninvasive treatment option for primary liver cancer and metastatic disease occurring in the liver. Although SBRT can be highly effective for establishing local control in hepatic malignancies, a tradeoff exists between tumor control and normal tissue complications. The objective of the present study was to review the normal tissue dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and derive normal tissue complication probability models.

Original language	English
Pages (from-to)	196-205
Number of pages	10
Journal	International Journal of Radiation Oncology Biology Physics
Volume	110
Issue number	1
DOIs	https://doi.org/10.1016/j.ijrobp.2017.12.290
State	Published - 1 May 2021
Externally published	Yes

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Miften, M., Vinogradskiy, Y., Moiseenko, V., Grimm, J., Yorke, E., Jackson, A., Tomé, W. A., Ten Haken, R. K., Ohri, N., Méndez Romero, A., Goodman, K. A., Marks, L. B., Kavanagh, B., & Dawson, L. A. (2021). Radiation Dose-Volume Effects for Liver SBRT. International Journal of Radiation Oncology Biology Physics, 110(1), 196-205. https://doi.org/10.1016/j.ijrobp.2017.12.290

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title = "Radiation Dose-Volume Effects for Liver SBRT",

abstract = "Stereotactic body radiation therapy (SBRT) has emerged as an effective, noninvasive treatment option for primary liver cancer and metastatic disease occurring in the liver. Although SBRT can be highly effective for establishing local control in hepatic malignancies, a tradeoff exists between tumor control and normal tissue complications. The objective of the present study was to review the normal tissue dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and derive normal tissue complication probability models.",

author = "Moyed Miften and Yevgeniy Vinogradskiy and Vitali Moiseenko and Jimm Grimm and Ellen Yorke and Andrew Jackson and Tom{\'e}, \{Wolfgang A.\} and \{Ten Haken\}, \{Randall K.\} and Nitin Ohri and \{M{\'e}ndez Romero\}, Alejandra and Goodman, \{Karyn A.\} and Marks, \{Lawrence B.\} and Brian Kavanagh and Dawson, \{Laura A.\}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2021",

month = may,

day = "1",

doi = "10.1016/j.ijrobp.2017.12.290",

language = "English",

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pages = "196--205",

journal = "International Journal of Radiation Oncology Biology Physics",

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AU - Miften, Moyed

AU - Vinogradskiy, Yevgeniy

AU - Moiseenko, Vitali

AU - Grimm, Jimm

AU - Yorke, Ellen

AU - Jackson, Andrew

AU - Tomé, Wolfgang A.

AU - Ten Haken, Randall K.

AU - Ohri, Nitin

AU - Méndez Romero, Alejandra

AU - Goodman, Karyn A.

AU - Marks, Lawrence B.

AU - Kavanagh, Brian

AU - Dawson, Laura A.

PY - 2021/5/1

Y1 - 2021/5/1

N2 - Stereotactic body radiation therapy (SBRT) has emerged as an effective, noninvasive treatment option for primary liver cancer and metastatic disease occurring in the liver. Although SBRT can be highly effective for establishing local control in hepatic malignancies, a tradeoff exists between tumor control and normal tissue complications. The objective of the present study was to review the normal tissue dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and derive normal tissue complication probability models.

AB - Stereotactic body radiation therapy (SBRT) has emerged as an effective, noninvasive treatment option for primary liver cancer and metastatic disease occurring in the liver. Although SBRT can be highly effective for establishing local control in hepatic malignancies, a tradeoff exists between tumor control and normal tissue complications. The objective of the present study was to review the normal tissue dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and derive normal tissue complication probability models.

UR - https://www.scopus.com/pages/publications/85042373677

U2 - 10.1016/j.ijrobp.2017.12.290

DO - 10.1016/j.ijrobp.2017.12.290

M3 - Article

C2 - 29482870

AN - SCOPUS:85042373677

SN - 0360-3016

VL - 110

SP - 196

EP - 205

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

IS - 1

ER -

Radiation Dose-Volume Effects for Liver SBRT

Abstract

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