Radiation dose reduction in CT-guided spine biopsies does not reduce diagnostic yield

K. A. Shpilberg, B. N. Delman, L. N. Tanenbaum, S. J. Esses, R. Subramaniam, A. H. Doshi

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


BACKGROUND AND PURPOSE: CT-guided biopsy is the most commonly used method to obtain tissue for diagnosis in suspected cases of malignancy involving the spine. The purpose of this study was to demonstrate that a low-dose CT-guided spine biopsy protocol is as effective in tissue sampling as a regular-dose protocol, without adversely affecting procedural time or complication rates. MATERIALS AND METHODS: We retrospectively reviewed all patients who underwent CT-guided spine procedures at our institution between May 2010 and October 2013. Biopsy duration, total number of scans, total volume CT dose index, total dose-length product, and diagnostic tissue yield of low-dose and regular-dose groups were compared. RESULTS: Sixty-four patients were included, of whom 31 underwent low-dose and 33 regular-dose spine biopsies. There was a statistically significant difference in total volume CT dose index and total dose-length product between the low-dose and regular-dose groups (P < .0001). There was no significant difference in the total number of scans obtained (P=.3385), duration of procedure (P=.149), or diagnostic tissue yield (P = .6017). CONCLUSIONS: Use of a low-dose CT-guided spine biopsy protocol is a practical alternative to regular-dose approaches, maintaining overall quality and efficiency at reduced ionizing radiation dose.

Original languageEnglish
Pages (from-to)2243-2247
Number of pages5
JournalAmerican Journal of Neuroradiology
Issue number12
StatePublished - 1 Dec 2014


Dive into the research topics of 'Radiation dose reduction in CT-guided spine biopsies does not reduce diagnostic yield'. Together they form a unique fingerprint.

Cite this