Racial disparities in chronic total occlusionpercutaneous coronary interventions: Insights from the PROGRESS-CTO Registry

Objectives. There is limited data on race and outcomes of chronic total occlusion (CTO) percutaneous coronary intervention(PCI). The authors sought to evaluate CTO PCI techniques and outcomes in different racial groups. Methods. We examined the baseline characteristics and procedural outcomes of 11 806 CTO PCIs performed at 44 US andnon-US centers between 2012 and March 2023. In-hospital major adverse cardiac events (MACE) included death,myocardial infarction, repeat target-vessel revascularization, pericardiocentesis, cardiac surgery, and stroke prior todischarge. Results. The most common racial group was White (84.5%), followed by Black (5.7%), "Other" (3.9%), Hispanic (2.9%),Asian (2.4%), and Native American (0.7%). There were significant differences in the baseline characteristics betweendifferent racial groups. When compared with non-White patients, the retrograde approach and antegrade dissection re-entrywere more likely to be the successful crossing strategies in White patients without any significant differences in technicalsuccess (86.4% vs 86.4%; P = .93), procedural success (84.8% vs 85.0%; P = .79), and in-hospital MACE (2.0% vs 1.5%; P= .15) between the 2 groups. The technical success rate was significantly higher in the "Other" racial group (91.0% vs 86.4%in White, 86.9% in Asian, 84.5% in Black, 84.5% in Hispanic, and 83.3% in Native American; P = .03) without any significantdifferences in procedural success or in-hospital MACE rates between the groups. Conclusions. Despite differences in baseline characteristics and procedural techniques, the procedural success and in-hospital MACE of CTO PCI were not significantly different between most racial groups. 2024 HMP Global. All Rights Reserved.