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Quinidine Revisited

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49 Scopus citations

Abstract

One of the earliest antiarrhythmic drugs developed, quinidine had a significant role in the treatment of many arrhythmias. After concerns for increased risk of ventricular arrhythmia and death with quinidine emerged, the use of quinidine fell dramatically in favor of newer antiarrhythmic medications. However, recent trials have generated renewed interest in the use of quinidine. In particular, quinidine appears to be safe and efficacious in combination with verapamil for the treatment of atrial fibrillation. Quinidine has also been used successfully to treat idiopathic ventricular fibrillation, Brugada syndrome, and Short QT syndrome. Although it is one of the oldest drugs in our armamentarium, quinidine continues to have a role in modern cardiology.

Original languageEnglish
Pages (from-to)317-321
Number of pages5
JournalAmerican Journal of Medicine
Volume122
Issue number4
DOIs
StatePublished - Apr 2009
Externally publishedYes

Keywords

  • Antiarrhythmic drug therapy
  • Arrhythmia
  • Atrial fibrillation
  • Brugada syndrome
  • Idiopathic ventricular fibrillation
  • Quinidine
  • Short QT syndrome

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