TY - JOUR
T1 - Quickly moving too slowly
T2 - Interneuron migration in Timothy Syndrome
AU - Fernando, Michael B.
AU - Brennand, Kristen J.
N1 - Publisher Copyright:
Copyright © 2022 Elsevier Inc. All rights reserved.
PY - 2022/2/3
Y1 - 2022/2/3
N2 - Aberrant migration of GABAergic interneurons during cortical neurodevelopment is implicated in Timothy Syndrome, yet the underlying mechanisms remain elusive. In this issue of Cell Stem Cell, Birey et al. model developing brain circuitry using "assembloids" from patients, characterizing a bimodal mechanism of mechano-chemically driven interneuron migration inefficiencies.
AB - Aberrant migration of GABAergic interneurons during cortical neurodevelopment is implicated in Timothy Syndrome, yet the underlying mechanisms remain elusive. In this issue of Cell Stem Cell, Birey et al. model developing brain circuitry using "assembloids" from patients, characterizing a bimodal mechanism of mechano-chemically driven interneuron migration inefficiencies.
UR - http://www.scopus.com/inward/record.url?scp=85124175229&partnerID=8YFLogxK
U2 - 10.1016/j.stem.2022.01.004
DO - 10.1016/j.stem.2022.01.004
M3 - Comment/debate
C2 - 35120616
AN - SCOPUS:85124175229
SN - 1934-5909
VL - 29
SP - 181
EP - 183
JO - Cell Stem Cell
JF - Cell Stem Cell
IS - 2
ER -