@inproceedings{e66cb338e13c4f2294816cbda7781073,
title = "Quantitative functional MRI of the visual cortex as a function of luminance contrast at 1.5 T",
abstract = "This study examined the BOLD signal changes in primary visual cortex as a function of luminous contrast at 1.5 T in 4 normals and 2 patients with multiple sclerosis (MS) disease. Echo planar T2* weighted BOLD imaging experiments were performed using a 1.5 T Imager. Ten axial slices through the calcarine fissure were obtained. The imaging series consisted of alternations between a 20-second epoch of dark screen (rest) and a 20-second epoch of a flickering checkerboard (activation) repeated 6 times. Each imaging series utilized a stepwise, graded increase of eight different luminance contrast levels. A paired t-test was used to compare the control condition with each activation condition. The data shows a linear trend in the number of fMRI activated voxels within the visual cortex with increasing luminous contrast in normals and MS patients. This study demonstrates quantifiable changes in BOLD signal and a linear increase in activated voxels within the primary visual cortex with increasing luminous contrast.",
author = "Faro, {S. H.} and Mohamed, {F. B.} and Tracy, {J. I.} and A. Pinus and F. Lublin and R. Elfont and R. Koenigsberg and Tsai, {F. Y.}",
year = "1999",
language = "English",
isbn = "0780356756",
series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
publisher = "IEEE",
pages = "1082",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
note = "Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) ; Conference date: 13-10-1999 Through 16-10-1999",
}