Quantitative and qualitative spectral domain optical coherence tomography analysis of subretinal deposits in patients with acute central serous retinopathy

Gennady Landa, Jonathan A. Barnett, Patricia M.T. Garcia, Katy W. Tai, Richard B. Rosen

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Purpose: To perform qualitative and quantitative analyses of subretinal protein deposits (PDs), seen in acute central serous retinopathy (CSR) patients, using high-resolution spectral domain optical coherence tomography (SD-OCT), in order to investigate whether the present PDs have any significant impact on best corrected visual acuity (BCVA). Methods: Patients diagnosed with acute CSR were included. Using SD-OCT, the following distances/heights were measured: central total retinal thickness, central neurosensory retinal thickness, the vertical and horizontal length of subfoveal subretinal fluid and subfoveal thickness of the PD layer, if present and could be measured. Results: Thirty-eight patients with acute CSR were included. A significant correlation was found between the subfoveal thickness of the PD layer and baseline/final visual acuities in the eyes (r = 0.60, p ≤ 0.001 and r = 0.45, p = 0.008, respectively). Conclusions: The thickness of subfoveal PDs at baseline appears to be an important parameter related to the BCVA and time of CSR resolution.

Original languageEnglish
Pages (from-to)62-68
Number of pages7
JournalOphthalmologica
Volume230
Issue number2
DOIs
StatePublished - Aug 2013
Externally publishedYes

Keywords

  • Central serous retinopathy
  • Spectral domain optical coherence tomography

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