Quality improvement project of a massive transfusion protocol (Mtp) to reduce wastage of blood components

Matteo Paganini, Hesham Abowali, Gerardo Bosco, Maha Balouch, Garrett Enten, Jin Deng, Aryeh Shander, David Ciesla, Jason Wilson, Enrico Camporesi

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1 Scopus citations


Massive transfusion protocols (MTPs) facilitate the organized delivery of blood components for traumatically injured patients. MTPs vary across institutions, and ratios of blood components can change during clinical management. As a result, significant amounts of components can be wasted. We completed a review of all MTP activations from 2015 to 2018, providing an in-depth analysis of waste in our single Level 1 trauma center. An interdepartmental group analyzed patterns of blood component wastage to guide three quality improvement initiatives. Specifically, we (1) completed a digital timeline for each MTP activation and termination, (2) improved communications between departments, and (3) provided yearly training for all personnel about MTP deployment. The analysis identified an association between delayed MTP deactivations and waste (RR=1.48, CI 1.19-1.85, p=0.0005).Anoverallimprovementinwastewasseenovertheyears,butthiscouldnotbeattributed to increased closed-loop communication as determined by the proportion of non-stop activations (F(124,3)=0.98, not significant). Delayed MTP deactivations are the primary determinant of blood component waste. Our proactive intervention on communications between groups was not sufficient in reducing the number of delayed deactivations. However, implementing a digital timeline and regular repetitive training yielded a significant reduction in wasted blood components.

Original languageEnglish
Article number274
Pages (from-to)1-9
Number of pages9
JournalInternational Journal of Environmental Research and Public Health
Issue number1
StatePublished - 1 Jan 2021
Externally publishedYes


  • Blood component transfusion
  • MTP
  • Massive transfusion protocol
  • Quality improvement
  • Waste


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