Quadruplet pregnancy: Two sets of twins, each occupying a horn of a septate (complete) uterus

Over the last decade, as both assisted reproductive technologies and diagnostic imaging techniques have improved, a greater number of unusual pregnancies have been documented. Quadruplet pregnancies are no longer a rare event in busy perinatal centers. However, this case report is unusual because the quadruplet pregnancy consisted of a pair of dichorionic/diamniotic twins, each in a horn of an anomalous uterus (septate-complete, with 2 cervices and an upper vaginal septum). Three-dimensional (3D) sonography was used to evaluate the location of the fetuses within the uterine horns. To our knowledge, no identical or similar case was reported in the literature, as reviewed by us in a PubMed search.