Pyroglutamyl diazomethyl ketone: Potent inhibitor of mammalian pyroglutamyl peptide hydrolase

Keyphrases

• Potent Inhibitor 100%
• Ketones 100%
• Peptide Hydrolases 100%
• Pyroglutamyl Peptide 100%
• Active Sites 33%
• Order of Magnitude 33%
• Metabolism 33%
• Physiological Role 33%
• Cysteine Protease 33%
• Endopeptidase 33%
• Thyrotropin 33%
• Site-directed 33%
• Pre-incubation 33%
• Nanomolar Concentrations 33%
• Bovine Brain 33%
• Inhibitor Concentration 33%
• Exopeptidase 33%
• Brain Enzymes 33%
• Rapid Inactivation 33%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Peptidase 100%
• Active Site 33%
• Metabolic Pathway 33%
• N-Terminus 33%
• Cysteine Protease 33%
• Exopeptidase 33%
• Thyrotropin-Releasing Hormone 33%
• Protease 33%

Pharmacology, Toxicology and Pharmaceutical Science

• 5 Oxoprolyl Peptidase 100%
• Proteinase 50%
• Cysteine Proteinase 50%
• Exopeptidase 50%
• Brain Enzyme 50%
• Protirelin 50%