Abstract
Epidemiological evidence suggests that environmental pollutants contribute to atopic dermatitis, but mechanistic details are currently lacking. Elentner et al. show that PXR, a key transcription factor involved in pollutant metabolism, drives features of subclinical atopic dermatitis. These observations provide new insight into how environmental insults may predispose individuals to atopic dermatitis.
Original language | English |
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Pages (from-to) | 8-10 |
Number of pages | 3 |
Journal | Journal of Investigative Dermatology |
Volume | 138 |
Issue number | 1 |
DOIs |
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State | Published - Jan 2018 |
Externally published | Yes |