PXR: A New Player in Atopic Dermatitis

Landon K. Oetjen, Anna M. Trier, Brian S. Kim

Research output: Contribution to journalComment/debate

5 Scopus citations

Abstract

Epidemiological evidence suggests that environmental pollutants contribute to atopic dermatitis, but mechanistic details are currently lacking. Elentner et al. show that PXR, a key transcription factor involved in pollutant metabolism, drives features of subclinical atopic dermatitis. These observations provide new insight into how environmental insults may predispose individuals to atopic dermatitis.

Original languageEnglish
Pages (from-to)8-10
Number of pages3
JournalJournal of Investigative Dermatology
Volume138
Issue number1
DOIs
StatePublished - Jan 2018
Externally publishedYes

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