Pulmonary embolus related to PC-SPES use in a patient with PSA recurrence after radical prostatectomy

Jonathan D. Schiff, Wendy S. Ziecheck, Benjamin Choi

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Patients diagnosed with a rising prostate-specific antigen level after radical prostatectomy represent a therapeutic dilemma. Herbal therapies including PC-SPES have gained popularity as alternatives to conventional hormonal ablation in such patients as a result of the perceived benefits of using natural products and proven clinical response in decreasing prostate-specific antigen levels. PC-SPES is one of the most popular herbs with known estrogenic activity in vitro and in vivo. Estrogenic compounds increase the risk of thromboembolic events. However, no specific guidelines are available with regard to the risk of thromboembolic events for patients using PC-SPES. We report a case of a patient treated with PC-SPES for prostate-specific antigen recurrence after radical prostatectomy who presented with pulmonary embolus and a right common femoral deep venous thrombus.

Original languageEnglish
Pages (from-to)444vii
JournalUrology
Volume59
Issue number3
DOIs
StatePublished - 2002
Externally publishedYes

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