PU.1 takes control of the dendritic cell lineage

Miriam Merad

doi:10.1016/j.immuni.2010.05.006

PU.1 takes control of the dendritic cell lineage

Miriam Merad

Marc and Jennifer Lipschultz Precision Immunology Institute

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Despite the importance of the cytokine receptor flt3 in dendritic cell (DC) homeostasis, little is known about its regulation during DC development. In this issue of Immunity, Carotta et al. (2010) reveal that the transcription factor PU.1 controls Flt3 expression in hematopoietic progenitors in a dose-dependent manner.

Original language	English
Pages (from-to)	583-585
Number of pages	3
Journal	Immunity
Volume	32
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2010.05.006
State	Published - May 2010

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title = "PU.1 takes control of the dendritic cell lineage",

abstract = "Despite the importance of the cytokine receptor flt3 in dendritic cell (DC) homeostasis, little is known about its regulation during DC development. In this issue of Immunity, Carotta et al. (2010) reveal that the transcription factor PU.1 controls Flt3 expression in hematopoietic progenitors in a dose-dependent manner.",

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AB - Despite the importance of the cytokine receptor flt3 in dendritic cell (DC) homeostasis, little is known about its regulation during DC development. In this issue of Immunity, Carotta et al. (2010) reveal that the transcription factor PU.1 controls Flt3 expression in hematopoietic progenitors in a dose-dependent manner.

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DO - 10.1016/j.immuni.2010.05.006

M3 - Short survey

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SN - 1074-7613

VL - 32

SP - 583

EP - 585

JO - Immunity

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PU.1 takes control of the dendritic cell lineage

Abstract

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