PTSD Biomarker Database: Deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools

Daniel Domingo-Fernández; Allison Provost; Alpha Tom Kodamullil; Josep Marín-Llaó; Heather Lasseter; Kristophe Diaz; Nikolaos P. Daskalakis; Lee Lancashire; Martin Hofmann-Apitius; Magali Haas

doi:10.1093/database/baz081

PTSD Biomarker Database: Deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools

Daniel Domingo-Fernández
, Allison Provost
, Alpha Tom Kodamullil
, Josep Marín-Llaó
, Heather Lasseter
, Kristophe Diaz
, Nikolaos P. Daskalakis
, Lee Lancashire
, Martin Hofmann-Apitius
, Magali Haas

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The PTSD Biomarker Database (PTSDDB) is a database that provides a landscape view of physiological markers being studied as putative biomarkers in the current post-traumatic stress disorder (PTSD) literature to enable researchers to explore and compare findings quickly. The PTSDDB currently contains over 900 biomarkers and their relevant information from 109 original articles published from 1997 to 2017. Further, the curated content stored in this database is complemented by a web application consisting of multiple interactive visualizations that enable the investigation of biomarker knowledge in PTSD (e.g. clinical study metadata, biomarker findings, experimental methods, etc.) by compiling results from biomarker studies to visualize the level of evidence for single biomarkers and across functional categories. This resource is the first attempt, to the best of our knowledge, to capture and organize biomarker and metadata in the area of PTSD for storage in a comprehensive database that may, in turn, facilitate future analysis and research in the field.

Original language	English
Article number	baz081
Journal	Database : the journal of biological databases and curation
Volume	2019
Issue number	1
DOIs	https://doi.org/10.1093/database/baz081
State	Published - 2019
Externally published	Yes

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Domingo-Fernández, D., Provost, A., Kodamullil, A. T., Marín-Llaó, J., Lasseter, H., Diaz, K., Daskalakis, N. P., Lancashire, L., Hofmann-Apitius, M., & Haas, M. (2019). PTSD Biomarker Database: Deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools. Database : the journal of biological databases and curation, 2019(1), Article baz081. https://doi.org/10.1093/database/baz081

@article{ed064f2d37904c118cf24bcfe4547dc4,

title = "PTSD Biomarker Database: Deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools",

abstract = "The PTSD Biomarker Database (PTSDDB) is a database that provides a landscape view of physiological markers being studied as putative biomarkers in the current post-traumatic stress disorder (PTSD) literature to enable researchers to explore and compare findings quickly. The PTSDDB currently contains over 900 biomarkers and their relevant information from 109 original articles published from 1997 to 2017. Further, the curated content stored in this database is complemented by a web application consisting of multiple interactive visualizations that enable the investigation of biomarker knowledge in PTSD (e.g. clinical study metadata, biomarker findings, experimental methods, etc.) by compiling results from biomarker studies to visualize the level of evidence for single biomarkers and across functional categories. This resource is the first attempt, to the best of our knowledge, to capture and organize biomarker and metadata in the area of PTSD for storage in a comprehensive database that may, in turn, facilitate future analysis and research in the field.",

author = "Daniel Domingo-Fern{\'a}ndez and Allison Provost and Kodamullil, \{Alpha Tom\} and Josep Mar{\'i}n-Lla{\'o} and Heather Lasseter and Kristophe Diaz and Daskalakis, \{Nikolaos P.\} and Lee Lancashire and Martin Hofmann-Apitius and Magali Haas",

note = "Publisher Copyright: {\textcopyright} 2019 The Author(s) 2019. Published by Oxford University Press.",

year = "2019",

doi = "10.1093/database/baz081",

language = "English",

volume = "2019",

journal = "Database : the journal of biological databases and curation",

issn = "1758-0463",

publisher = "Oxford University Press",

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Domingo-Fernández, D, Provost, A, Kodamullil, AT, Marín-Llaó, J, Lasseter, H, Diaz, K, Daskalakis, NP, Lancashire, L, Hofmann-Apitius, M & Haas, M 2019, 'PTSD Biomarker Database: Deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools', Database : the journal of biological databases and curation, vol. 2019, no. 1, baz081. https://doi.org/10.1093/database/baz081

TY - JOUR

T1 - PTSD Biomarker Database

T2 - Deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools

AU - Domingo-Fernández, Daniel

AU - Provost, Allison

AU - Kodamullil, Alpha Tom

AU - Marín-Llaó, Josep

AU - Lasseter, Heather

AU - Diaz, Kristophe

AU - Daskalakis, Nikolaos P.

AU - Lancashire, Lee

AU - Hofmann-Apitius, Martin

AU - Haas, Magali

PY - 2019

Y1 - 2019

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AB - The PTSD Biomarker Database (PTSDDB) is a database that provides a landscape view of physiological markers being studied as putative biomarkers in the current post-traumatic stress disorder (PTSD) literature to enable researchers to explore and compare findings quickly. The PTSDDB currently contains over 900 biomarkers and their relevant information from 109 original articles published from 1997 to 2017. Further, the curated content stored in this database is complemented by a web application consisting of multiple interactive visualizations that enable the investigation of biomarker knowledge in PTSD (e.g. clinical study metadata, biomarker findings, experimental methods, etc.) by compiling results from biomarker studies to visualize the level of evidence for single biomarkers and across functional categories. This resource is the first attempt, to the best of our knowledge, to capture and organize biomarker and metadata in the area of PTSD for storage in a comprehensive database that may, in turn, facilitate future analysis and research in the field.

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U2 - 10.1093/database/baz081

DO - 10.1093/database/baz081

M3 - Article

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AN - SCOPUS:85068994081

SN - 1758-0463

VL - 2019

JO - Database : the journal of biological databases and curation

JF - Database : the journal of biological databases and curation

IS - 1

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ER -

PTSD Biomarker Database: Deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools

Abstract

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