Psychotherapy and psychopharmacology should be considered as 2 alternative or complementary treatment approaches, not as antithetical to each other. Studies of potential negative interactions of these 2 techniques have demonstrated none. A number of positive benefits have, however, been found. Studies that look at combined treatments have generally been restricted to depression. Some, but not all, studies suggest an advantage for the combination, particularly in severe, recurrent, chronic, and geriatric depressions.