TY - JOUR
T1 - Psychiatric comorbidities in epilepsy
AU - Josephson, Colin B.
AU - Jetté, Nathalie
N1 - Publisher Copyright:
© 2017 Institute of Psychiatry and Johns Hopkins University.
PY - 2017/9/3
Y1 - 2017/9/3
N2 - Psychiatric comorbidities, including mood, anxiety, and psychotic disorders, are common in epilepsy, often occurring at rates 2–3-fold or higher than in the general population without epilepsy. This article discusses the epidemiology of psychiatric disorders in epilepsy, hypotheses regarding the pathogenesis of these comorbidities, and treatment implications. More specifically, it addresses: (1) How common are major depressive disorder, anxiety disorders, and psychotic disorders in epilepsy? (2) How does one screen for these psychiatric disorders in persons with epilepsy? (3) Why do psychiatric conditions occur in epilepsy? (4) Is the treatment of psychiatric comorbidity in epilepsy associated with seizures? The important topic of suicide and suicidal ideation in epilepsy, risk factors for their occurrence, and how to screen for these co-existent conditions is also discussed. Finally, gaps in knowledge regarding psychiatric conditions in epilepsy are briefly discussed.
AB - Psychiatric comorbidities, including mood, anxiety, and psychotic disorders, are common in epilepsy, often occurring at rates 2–3-fold or higher than in the general population without epilepsy. This article discusses the epidemiology of psychiatric disorders in epilepsy, hypotheses regarding the pathogenesis of these comorbidities, and treatment implications. More specifically, it addresses: (1) How common are major depressive disorder, anxiety disorders, and psychotic disorders in epilepsy? (2) How does one screen for these psychiatric disorders in persons with epilepsy? (3) Why do psychiatric conditions occur in epilepsy? (4) Is the treatment of psychiatric comorbidity in epilepsy associated with seizures? The important topic of suicide and suicidal ideation in epilepsy, risk factors for their occurrence, and how to screen for these co-existent conditions is also discussed. Finally, gaps in knowledge regarding psychiatric conditions in epilepsy are briefly discussed.
KW - Mental health
KW - anxiety
KW - depression
KW - epidemiology
KW - psychosis
UR - http://www.scopus.com/inward/record.url?scp=85029624975&partnerID=8YFLogxK
U2 - 10.1080/09540261.2017.1302412
DO - 10.1080/09540261.2017.1302412
M3 - Review article
C2 - 28681667
AN - SCOPUS:85029624975
SN - 0954-0261
VL - 29
SP - 409
EP - 424
JO - International Review of Psychiatry
JF - International Review of Psychiatry
IS - 5
ER -