Psoriatic arthritis and arthroplasty: A review of the literature

Ilya Iofin, Brett Levine, Neil Badlani, Gregg R. Klein, William L. Jaffe

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Psoriatic arthritis is an inflammatory arthropathy associated with the characteristic dermatologic lesions of psoriasis. The diagnosis of psoriatic arthritis is quite difficult, due to the overlap of patients with osteoarthritis (OA) or rheumatoid arthritis (RA) with concomitant non-associated psoriasis. A nonspecific elevation in inflammatory markers (erythrocyte sedimentation rate, ESR; antinuclear antibodies, ANA; or rheumatoid factor, RF) and characteristic radiographic features are often present in these patients. The mainstay of treatment is medical management, using NSAIDs, various immunosuppressants, and anti-TNF agents, for both pain control and possibly as disease modifying agents. Only a minority of patients require surgical intervention, leading to the limited amount of literature concerning total joint arthroplasty and psoriatic arthritis. While past literature has yielded high infection rates post-arthroplasty, newer studies have found more promising results. Alternative surgical options for treating destructive arthritis include open or arthroscopic synovectomy. While early results are promising, recurrence rates and long-term outcomes are not yet available.

Original languageEnglish
Pages (from-to)41-48
Number of pages8
JournalBulletin of the NYU hospital for joint diseases
Issue number1
StatePublished - 2008
Externally publishedYes


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