Pseudoxanthoma Elasticum and Mitral-Valve Prolapse

Reed E. Pyeritz; James L. Weiss; William A. Renie; Sturart L. Fine; Mark G. Lebwohl; Douglas Distefano; Philip G. Prioleau; Martin Uram; Lawrence A. Yannuzzi; Raul Fleischmajer

doi:10.1056/NEJM198212023072315

Pseudoxanthoma Elasticum and Mitral-Valve Prolapse

Reed E. Pyeritz, James L. Weiss, William A. Renie, Sturart L. Fine, Mark G. Lebwohl, Douglas Distefano, Philip G. Prioleau, Martin Uram, Lawrence A. Yannuzzi, Raul Fleischmajer

Research output: Contribution to journal › Letter › peer-review

16 Scopus citations

Abstract

To the Editor: Lebwohl and colleagues¹ performed M-mode echocardiography on 14 patients affected by pseudoxanthoma elasticum and found mitral-valve prolapse in 11 (71 per cent) (July 22 issue). We are conducting a multidisciplinary assessment of pseudoxanthoma elasticum. Preliminary results (unpublished) of cardiologic examinations in 28 unrelated patients do not confirm this high prevalence of mitral-valve prolapse. None of the 17 women or 11 men (mean age, 43.3 years; range, 13 to 71 years) hada systolic click, and only one had an apical systolic murmur. M-mode echocardiograms in 16 patients showed mitral-valve prolapse in 1. Two-dimensional echocardiograms in 26 patients.

Original language	English
Pages (from-to)	1451-1452
Number of pages	2
Journal	New England Journal of Medicine
Volume	307
Issue number	23
DOIs	https://doi.org/10.1056/NEJM198212023072315
State	Published - 2 Dec 1982

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title = "Pseudoxanthoma Elasticum and Mitral-Valve Prolapse",

abstract = "To the Editor: Lebwohl and colleagues1 performed M-mode echocardiography on 14 patients affected by pseudoxanthoma elasticum and found mitral-valve prolapse in 11 (71 per cent) (July 22 issue). We are conducting a multidisciplinary assessment of pseudoxanthoma elasticum. Preliminary results (unpublished) of cardiologic examinations in 28 unrelated patients do not confirm this high prevalence of mitral-valve prolapse. None of the 17 women or 11 men (mean age, 43.3 years; range, 13 to 71 years) hada systolic click, and only one had an apical systolic murmur. M-mode echocardiograms in 16 patients showed mitral-valve prolapse in 1. Two-dimensional echocardiograms in 26 patients.",

author = "Pyeritz, \{Reed E.\} and Weiss, \{James L.\} and Renie, \{William A.\} and Fine, \{Sturart L.\} and Lebwohl, \{Mark G.\} and Douglas Distefano and Prioleau, \{Philip G.\} and Martin Uram and Yannuzzi, \{Lawrence A.\} and Raul Fleischmajer",

year = "1982",

month = dec,

day = "2",

doi = "10.1056/NEJM198212023072315",

language = "English",

volume = "307",

pages = "1451--1452",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachussetts Medical Society",

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TY - JOUR

T1 - Pseudoxanthoma Elasticum and Mitral-Valve Prolapse

AU - Pyeritz, Reed E.

AU - Weiss, James L.

AU - Renie, William A.

AU - Fine, Sturart L.

AU - Lebwohl, Mark G.

AU - Distefano, Douglas

AU - Prioleau, Philip G.

AU - Uram, Martin

AU - Yannuzzi, Lawrence A.

AU - Fleischmajer, Raul

PY - 1982/12/2

Y1 - 1982/12/2

N2 - To the Editor: Lebwohl and colleagues1 performed M-mode echocardiography on 14 patients affected by pseudoxanthoma elasticum and found mitral-valve prolapse in 11 (71 per cent) (July 22 issue). We are conducting a multidisciplinary assessment of pseudoxanthoma elasticum. Preliminary results (unpublished) of cardiologic examinations in 28 unrelated patients do not confirm this high prevalence of mitral-valve prolapse. None of the 17 women or 11 men (mean age, 43.3 years; range, 13 to 71 years) hada systolic click, and only one had an apical systolic murmur. M-mode echocardiograms in 16 patients showed mitral-valve prolapse in 1. Two-dimensional echocardiograms in 26 patients.

AB - To the Editor: Lebwohl and colleagues1 performed M-mode echocardiography on 14 patients affected by pseudoxanthoma elasticum and found mitral-valve prolapse in 11 (71 per cent) (July 22 issue). We are conducting a multidisciplinary assessment of pseudoxanthoma elasticum. Preliminary results (unpublished) of cardiologic examinations in 28 unrelated patients do not confirm this high prevalence of mitral-valve prolapse. None of the 17 women or 11 men (mean age, 43.3 years; range, 13 to 71 years) hada systolic click, and only one had an apical systolic murmur. M-mode echocardiograms in 16 patients showed mitral-valve prolapse in 1. Two-dimensional echocardiograms in 26 patients.

UR - https://www.scopus.com/pages/publications/0020473808

U2 - 10.1056/NEJM198212023072315

DO - 10.1056/NEJM198212023072315

M3 - Letter

C2 - 7133103

AN - SCOPUS:0020473808

SN - 0028-4793

VL - 307

SP - 1451

EP - 1452

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 23

ER -

Pseudoxanthoma Elasticum and Mitral-Valve Prolapse

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