Pseudosarcomatous cystadenocarcinoma of the liver

Pamela D. Unger; Swan N. Thung; Mamoru Kaneko

doi:10.1016/S0046-8177(87)80038-2

Pseudosarcomatous cystadenocarcinoma of the liver

Pamela D. Unger, Swan N. Thung, Mamoru Kaneko

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Abstract

A case of papillary cystadenocarcinoma with spindle (pseudosarcomatous) metaplasia of the liver is described in a 64-year-old woman. This tumor was solitary, multiloculated, and had a fibrous pseudocapsule. It was composed of undifferentiated malignant epithelial cells, which lined cystic spaces, with sarcomatous cells underneath. Immunohistochemical studies showed no detectable α-feto-protein in the tumor; keratin was present in epithelial and spindle tumor cells, and α₁-antitrypsin was present in cytoplasm of many tumor cells. Intracytoplasmic periodic acid-Schiff-positive, diastase-resistant globules, some of them reactive for α₁-antitrypsin, were seen. A primary liver tumor with this histology has not been described previously in the literature.

Original language	English
Pages (from-to)	521-523
Number of pages	3
Journal	Human Pathology
Volume	18
Issue number	5
DOIs	https://doi.org/10.1016/S0046-8177(87)80038-2
State	Published - May 1987

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title = "Pseudosarcomatous cystadenocarcinoma of the liver",

abstract = "A case of papillary cystadenocarcinoma with spindle (pseudosarcomatous) metaplasia of the liver is described in a 64-year-old woman. This tumor was solitary, multiloculated, and had a fibrous pseudocapsule. It was composed of undifferentiated malignant epithelial cells, which lined cystic spaces, with sarcomatous cells underneath. Immunohistochemical studies showed no detectable α-feto-protein in the tumor; keratin was present in epithelial and spindle tumor cells, and α1-antitrypsin was present in cytoplasm of many tumor cells. Intracytoplasmic periodic acid-Schiff-positive, diastase-resistant globules, some of them reactive for α1-antitrypsin, were seen. A primary liver tumor with this histology has not been described previously in the literature.",

author = "Unger, {Pamela D.} and Thung, {Swan N.} and Mamoru Kaneko",

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AU - Unger, Pamela D.

AU - Thung, Swan N.

AU - Kaneko, Mamoru

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N2 - A case of papillary cystadenocarcinoma with spindle (pseudosarcomatous) metaplasia of the liver is described in a 64-year-old woman. This tumor was solitary, multiloculated, and had a fibrous pseudocapsule. It was composed of undifferentiated malignant epithelial cells, which lined cystic spaces, with sarcomatous cells underneath. Immunohistochemical studies showed no detectable α-feto-protein in the tumor; keratin was present in epithelial and spindle tumor cells, and α1-antitrypsin was present in cytoplasm of many tumor cells. Intracytoplasmic periodic acid-Schiff-positive, diastase-resistant globules, some of them reactive for α1-antitrypsin, were seen. A primary liver tumor with this histology has not been described previously in the literature.

AB - A case of papillary cystadenocarcinoma with spindle (pseudosarcomatous) metaplasia of the liver is described in a 64-year-old woman. This tumor was solitary, multiloculated, and had a fibrous pseudocapsule. It was composed of undifferentiated malignant epithelial cells, which lined cystic spaces, with sarcomatous cells underneath. Immunohistochemical studies showed no detectable α-feto-protein in the tumor; keratin was present in epithelial and spindle tumor cells, and α1-antitrypsin was present in cytoplasm of many tumor cells. Intracytoplasmic periodic acid-Schiff-positive, diastase-resistant globules, some of them reactive for α1-antitrypsin, were seen. A primary liver tumor with this histology has not been described previously in the literature.

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Pseudosarcomatous cystadenocarcinoma of the liver

Abstract

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