Proteomic study of anticancer activity of garlic oil in gastric cancer cells

Feifei Li, Xiaoli Feng, Yu Gao, Wenmei Li, Fengmei Zhang, Xiaolei Li, Youyong Lu, Siqi Liu, Rong Wang

Research output: Contribution to conferencePaperpeer-review

Abstract

The proteomic studies were conducted using the two human cancer cell lines, caucasian gastric adenocarcinoma cells and human gastric cancer BGC-823 cells treated with and without garlic oil. Both BGC-823 and AGS cells were cultured in 10 cm plate and treated with garlic oil for 72 hours. The control cells were cultured in the same conditions except treated with Tween -80 rather than garlic oil. A significant morphology changes both in cell shape and cell numbers were observed, after 3 days treatment with garlic oil. The results show that the identification of proteins corresponding to the garlic treatment revealed some of the potential molecular mechanism of garlic anticancer activities.

Original languageEnglish
Pages279-280
Number of pages2
StatePublished - 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: 2 Jun 20026 Jun 2002

Conference

ConferenceProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Country/TerritoryUnited States
CityOrlando, FL
Period2/06/026/06/02

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