Protein-losing enteropathy in ulcerative colitis

Ryan Ungaro, Mark W. Babyatsky, Hongfa Zhu, Jeffrey S. Freed

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Protein-losing enteropathy (PLE) is a debilitating potential complication of ulcerative colitis (UC). We report a case of PLE in a 26-year-old male patient with UC. The patient lost 50 pounds in the setting of a UC flare and was found to have an albumin level of 1.2 g/dl. Although the patient's UC was clinically controlled with steroids, the weight loss and hypoalbuminemia persisted with the patient's course complicated by development of deep vein thrombosis and pulmonary embolism. The diagnosis of PLE was confirmed with measurement of stool alpha-1-antitrypsin clearance. The patient's condition significantly improved following procto-colectomy.

Original languageEnglish
Pages (from-to)177-182
Number of pages6
JournalCase Reports in Gastroenterology
Issue number1
StatePublished - Jan 2012


  • Procto-colectomy
  • Protein-losing enteropathy
  • Ulcerative colitis


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