Protein C and S deficiency

Frank A. Nizzi; Harold S. Kaplan

doi:10.1055/s-2007-994930

Protein C and S deficiency

Frank A. Nizzi, Harold S. Kaplan

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Protein C and S deficiency states predispose affected individuals to thrombosis, especially venous thrombosis of the lower extremities, usually beginning in the teenage years. Treatment of these patients is generally with oral anticoagulation, following initial heparinization. The classification of the deficiency states is dependent upon determination of the quantity and functional activity of either protein.

Original language	English
Pages (from-to)	265-272
Number of pages	8
Journal	Seminars in Thrombosis and Hemostasis
Volume	25
Issue number	3
DOIs	https://doi.org/10.1055/s-2007-994930
State	Published - 1999
Externally published	Yes

Keywords

Protein C
Protein C deficiency
Protein S
Protein S deficiency
Thrombophilia
Thrombosis

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10.1055/s-2007-994930

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title = "Protein C and S deficiency",

abstract = "Protein C and S deficiency states predispose affected individuals to thrombosis, especially venous thrombosis of the lower extremities, usually beginning in the teenage years. Treatment of these patients is generally with oral anticoagulation, following initial heparinization. The classification of the deficiency states is dependent upon determination of the quantity and functional activity of either protein.",

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AU - Kaplan, Harold S.

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AB - Protein C and S deficiency states predispose affected individuals to thrombosis, especially venous thrombosis of the lower extremities, usually beginning in the teenage years. Treatment of these patients is generally with oral anticoagulation, following initial heparinization. The classification of the deficiency states is dependent upon determination of the quantity and functional activity of either protein.

KW - Protein C

KW - Protein C deficiency

KW - Protein S

KW - Protein S deficiency

KW - Thrombophilia

KW - Thrombosis

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U2 - 10.1055/s-2007-994930

DO - 10.1055/s-2007-994930

M3 - Article

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AN - SCOPUS:0032768594

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VL - 25

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EP - 272

JO - Seminars in Thrombosis and Hemostasis

JF - Seminars in Thrombosis and Hemostasis

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ER -

Protein C and S deficiency

Abstract

Keywords

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