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Prostate cancer cells promote osteoblastic bone metastases through Wnts
Christopher L. Hall
, Anna Bafico
, Jinlu Dai
,
Stuart A. Aaronson
, Evan T. Keller
Icahn School of Medicine at Mount Sinai
Cancer Mechanisms
Environmental Medicine
Graduate School of Biomedical Sciences
Institute for Exposomic Research
Medicine
Medicine - Hematology and Medical Oncology
Oncological Sciences
Mount Sinai Tisch Cancer Center
Research output
:
Contribution to journal
›
Article
›
peer-review
274
Scopus citations
Overview
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Keyphrases
Prostate Cancer Cells
100%
Wnts
100%
Dickkopf-1 (DKK1)
100%
Osteolytic Metastasis
100%
Osteoblastic Activity
62%
C4-2B
50%
Prostate Cancer
37%
PC-3 Cells
37%
Prostate Cancer Cell Lines
25%
Osteoblastic
25%
Osteolytic Lesions
25%
MRNA Expression
12%
Alkaline Phosphatase
12%
Short Hairpin RNA (shRNA)
12%
Non-neoplastic
12%
Human Mesenchymal Stem Cells (hMSCs)
12%
Large Families
12%
Osteolytic
12%
Primary Prostate Cancer
12%
Endogenous Protein
12%
Tibia
12%
Murine Bone Marrow
12%
PC-3
12%
Prostate Tissue
12%
In Vivo Model
12%
Expression Vector
12%
Bone Growth
12%
Wnt Inhibitors
12%
Osteogenic Tumor
12%
Osteogenic Factor
12%
Medicine and Dentistry
Cancer Cell
100%
Prostate Cancer
100%
Bone Metastasis
100%
Bone Development
62%
Prostate Cancer Cell Line
25%
Bone Atrophy
25%
Neoplasm
12%
Short Hairpin RNA
12%
Tibia
12%
Alkaline Phosphatase
12%
Bone Growth
12%
Prostate Tissue
12%
Expression Vector
12%
Bone Marrow Stromal Cell
12%
Mineralization
12%
Messenger RNA
12%