Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II)

Andrew Bauerschmidt; Nika Koshkelashvili; Celestine C. Ezeani; Ji Yeoun Yoo; Yan Zhang; Louis N. Manganas; Kailash Kapadia; Deanna Palenzuela; Christian C. Schmidt; Regina Lief; Bridget T. Kiely; Tenzin Choezom; Michael McClurkin; Andrew Shorten; Kamil Detyniecki; Lawrence J. Hirsch; Joseph T. Giacino; Hal Blumenfeld

doi:10.1016/j.yebeh.2012.10.022

Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II)

Andrew Bauerschmidt, Nika Koshkelashvili, Celestine C. Ezeani, Ji Yeoun Yoo, Yan Zhang, Louis N. Manganas, Kailash Kapadia, Deanna Palenzuela, Christian C. Schmidt, Regina Lief, Bridget T. Kiely, Tenzin Choezom, Michael McClurkin, Andrew Shorten, Kamil Detyniecki, Lawrence J. Hirsch, Joseph T. Giacino, Hal Blumenfeld

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Impaired consciousness in epilepsy has a significant negative impact on patients' quality of life yet is difficult to study objectively. Here, we develop an improved prospective Responsiveness in Epilepsy Scale-II (RES-II) and report initial results compared with the earlier version of the scale (RES). The RES-II is simpler to administer and includes both verbal and non-verbal test items. We evaluated 75 seizures (24 patients) with RES and 34 seizures (11 patients) with RES-II based on video-EEG review. The error rate per seizure by test administrators improved markedly from a mean of 2.01 ± 0.04 with RES to 0.24 ± 0.11 with RES-II. Performance during focal seizures showed a bimodal distribution, corresponding to the traditional complex partial vs. simple partial seizure classification. We conclude that RES-II has improved accuracy and testing efficiency compared with the original RES. Prospective objective testing will ultimately lead to a better understanding of the mechanisms of impaired consciousness in epilepsy.

Original language	English
Pages (from-to)	25-28
Number of pages	4
Journal	Epilepsy and Behavior
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/j.yebeh.2012.10.022
State	Published - Jan 2013
Externally published	Yes

Keywords

Behavioral testing
Consciousness
Epilepsy
Focal seizures
Generalized tonic-clonic seizures
Partial seizures

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10.1016/j.yebeh.2012.10.022

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Bauerschmidt, A., Koshkelashvili, N., Ezeani, C. C., Yoo, J. Y., Zhang, Y., Manganas, L. N., Kapadia, K., Palenzuela, D., Schmidt, C. C., Lief, R., Kiely, B. T., Choezom, T., McClurkin, M., Shorten, A., Detyniecki, K., Hirsch, L. J., Giacino, J. T., & Blumenfeld, H. (2013). Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II). Epilepsy and Behavior, 26(1), 25-28. https://doi.org/10.1016/j.yebeh.2012.10.022

@article{ed2ecbdccf264d87bfec4be85646b804,

title = "Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II)",

abstract = "Impaired consciousness in epilepsy has a significant negative impact on patients' quality of life yet is difficult to study objectively. Here, we develop an improved prospective Responsiveness in Epilepsy Scale-II (RES-II) and report initial results compared with the earlier version of the scale (RES). The RES-II is simpler to administer and includes both verbal and non-verbal test items. We evaluated 75 seizures (24 patients) with RES and 34 seizures (11 patients) with RES-II based on video-EEG review. The error rate per seizure by test administrators improved markedly from a mean of 2.01 ± 0.04 with RES to 0.24 ± 0.11 with RES-II. Performance during focal seizures showed a bimodal distribution, corresponding to the traditional complex partial vs. simple partial seizure classification. We conclude that RES-II has improved accuracy and testing efficiency compared with the original RES. Prospective objective testing will ultimately lead to a better understanding of the mechanisms of impaired consciousness in epilepsy.",

keywords = "Behavioral testing, Consciousness, Epilepsy, Focal seizures, Generalized tonic-clonic seizures, Partial seizures",

author = "Andrew Bauerschmidt and Nika Koshkelashvili and Ezeani, \{Celestine C.\} and Yoo, \{Ji Yeoun\} and Yan Zhang and Manganas, \{Louis N.\} and Kailash Kapadia and Deanna Palenzuela and Schmidt, \{Christian C.\} and Regina Lief and Kiely, \{Bridget T.\} and Tenzin Choezom and Michael McClurkin and Andrew Shorten and Kamil Detyniecki and Hirsch, \{Lawrence J.\} and Giacino, \{Joseph T.\} and Hal Blumenfeld",

note = "Funding Information: This work was supported by NIH R01 NS055829 , by the Patrick and Catherine Weldon Donaghue Medical Research Foundation and by the Betsy and Jonathan Blattmachr Family . Andrew Bauerschmidt was supported by the Doris Duke Charitable Foundation .",

year = "2013",

month = jan,

doi = "10.1016/j.yebeh.2012.10.022",

language = "English",

volume = "26",

pages = "25--28",

journal = "Epilepsy and Behavior",

issn = "1525-5050",

publisher = "Academic Press Inc.",

number = "1",

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Bauerschmidt, A, Koshkelashvili, N, Ezeani, CC, Yoo, JY, Zhang, Y, Manganas, LN, Kapadia, K, Palenzuela, D, Schmidt, CC, Lief, R, Kiely, BT, Choezom, T, McClurkin, M, Shorten, A, Detyniecki, K, Hirsch, LJ, Giacino, JT & Blumenfeld, H 2013, 'Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II)', Epilepsy and Behavior, vol. 26, no. 1, pp. 25-28. https://doi.org/10.1016/j.yebeh.2012.10.022

TY - JOUR

T1 - Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II)

AU - Bauerschmidt, Andrew

AU - Koshkelashvili, Nika

AU - Ezeani, Celestine C.

AU - Yoo, Ji Yeoun

AU - Zhang, Yan

AU - Manganas, Louis N.

AU - Kapadia, Kailash

AU - Palenzuela, Deanna

AU - Schmidt, Christian C.

AU - Lief, Regina

AU - Kiely, Bridget T.

AU - Choezom, Tenzin

AU - McClurkin, Michael

AU - Shorten, Andrew

AU - Detyniecki, Kamil

AU - Hirsch, Lawrence J.

AU - Giacino, Joseph T.

AU - Blumenfeld, Hal

N1 - Funding Information: This work was supported by NIH R01 NS055829 , by the Patrick and Catherine Weldon Donaghue Medical Research Foundation and by the Betsy and Jonathan Blattmachr Family . Andrew Bauerschmidt was supported by the Doris Duke Charitable Foundation .

PY - 2013/1

Y1 - 2013/1

N2 - Impaired consciousness in epilepsy has a significant negative impact on patients' quality of life yet is difficult to study objectively. Here, we develop an improved prospective Responsiveness in Epilepsy Scale-II (RES-II) and report initial results compared with the earlier version of the scale (RES). The RES-II is simpler to administer and includes both verbal and non-verbal test items. We evaluated 75 seizures (24 patients) with RES and 34 seizures (11 patients) with RES-II based on video-EEG review. The error rate per seizure by test administrators improved markedly from a mean of 2.01 ± 0.04 with RES to 0.24 ± 0.11 with RES-II. Performance during focal seizures showed a bimodal distribution, corresponding to the traditional complex partial vs. simple partial seizure classification. We conclude that RES-II has improved accuracy and testing efficiency compared with the original RES. Prospective objective testing will ultimately lead to a better understanding of the mechanisms of impaired consciousness in epilepsy.

AB - Impaired consciousness in epilepsy has a significant negative impact on patients' quality of life yet is difficult to study objectively. Here, we develop an improved prospective Responsiveness in Epilepsy Scale-II (RES-II) and report initial results compared with the earlier version of the scale (RES). The RES-II is simpler to administer and includes both verbal and non-verbal test items. We evaluated 75 seizures (24 patients) with RES and 34 seizures (11 patients) with RES-II based on video-EEG review. The error rate per seizure by test administrators improved markedly from a mean of 2.01 ± 0.04 with RES to 0.24 ± 0.11 with RES-II. Performance during focal seizures showed a bimodal distribution, corresponding to the traditional complex partial vs. simple partial seizure classification. We conclude that RES-II has improved accuracy and testing efficiency compared with the original RES. Prospective objective testing will ultimately lead to a better understanding of the mechanisms of impaired consciousness in epilepsy.

KW - Behavioral testing

KW - Consciousness

KW - Epilepsy

KW - Focal seizures

KW - Generalized tonic-clonic seizures

KW - Partial seizures

UR - https://www.scopus.com/pages/publications/84870571703

U2 - 10.1016/j.yebeh.2012.10.022

DO - 10.1016/j.yebeh.2012.10.022

M3 - Article

C2 - 23201609

AN - SCOPUS:84870571703

SN - 1525-5050

VL - 26

SP - 25

EP - 28

JO - Epilepsy and Behavior

JF - Epilepsy and Behavior

IS - 1

ER -

Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II)

Abstract

Keywords

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