Proposed classification of patient subgroups in Crohn's disease

D. B. Sachar, H. A. Andrews, R. G. Farmer, F. Pallone, A. S. Pena, C. Prantera, P. Rutgeerts

Research output: Contribution to journalReview articlepeer-review

157 Scopus citations


Clinical studies of Crohn's disease must rely upon homogeneity of patient subgroups. We do not believe that merely 'lumping' all cases into the Procrustean bed of a numerical index accomplishes this purpose. We therefore propose that all cases be described primarily by anatomical location (e.g. gastroduodenitis, jejunitis, ileitis, colitis, perianal disease, etc.) and anatomical extent (localised or diffuse), with modifiers for disease behaviour (primarily fibrostenotic, primarily inflammatory, or primarily fistulising) and operative history (primary or recurrent).

Original languageEnglish
Pages (from-to)141-154
Number of pages14
JournalGastroenterology International
Issue number3
StatePublished - 1992


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