Propofol combined with lorazepam for severe poly substance misuse and withdrawal states in intensive care unit: A case series and review

Kathirvels Subramaniam, R. M. Gowda, K. Jani, W. Zewedie, R. Ute

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A safe, rapid, and effective way to detoxify patients from substance misuse is important in facilitating further treatment of their psychiatric or substance use disorder. This paper discusses the treatment of acute withdrawal from polysubstance misuse in three patients in the intensive care unit setting using combined sedation with a benzodiazepine, lorazepam, and a general anaesthetic, propofol. Lorazepam alone was not effective in massive doses in these cases. The advantages and mechanism of action of using multiple agents to control refractory symptoms is discussed.

Original languageEnglish
Pages (from-to)632-634
Number of pages3
JournalEmergency Medicine Journal
Volume21
Issue number5
DOIs
StatePublished - Sep 2004
Externally publishedYes

Fingerprint

Dive into the research topics of 'Propofol combined with lorazepam for severe poly substance misuse and withdrawal states in intensive care unit: A case series and review'. Together they form a unique fingerprint.

Cite this