Prophylactic antibiotics in orthopaedic surgery.

Laura Prokuski, Terry A. Clyburn, Richard P. Evans, Calin S. Moucha

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The use of prophylactic antibiotics in orthopaedic surgery has been proven effective in reducing surgical site infections after hip and knee arthroplasty, spine procedures, and open reduction and internal fixation of fractures. To maximize the beneficial effect of prophylactic antibiotics, while minimizing any adverse effects, the correct antimicrobial agent must be selected, the drug must be administered just before incision, and the duration of administration should not exceed 24 hours.

Original languageEnglish
Pages (from-to)545-555
Number of pages11
JournalInstructional course lectures
Volume60
StatePublished - 2011

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