Progressive multifocal leukoencephalopathy-remission with cytarabine

T. O'Riordan; P. A. Daly; M. Hutchinson; A. G. Shattock; S. D. Gardner

doi:10.1016/S0163-4453(90)92324-E

Progressive multifocal leukoencephalopathy-remission with cytarabine

T. O'Riordan
, P. A. Daly
, M. Hutchinson
, A. G. Shattock
, S. D. Gardner

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

A 51-year-old women who was in complete remission from non-Hodgkin's lymphoma, developed a rapidly progressive dementia. Progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of a rising antibody titre to JC polyomavirus in cerebro-spinal fluid and serum and the presence of diffuse white matter changes on magnetic resonance imaging. She was treated initially with intravenous cytarabine and showed minimal improvement. Rapid improvement occurred when intrathecal cytarabine was added and the patient is in complete remission from both lymphoma and PML 20 months later.

Original language	English
Pages (from-to)	51-52,IN1-IN3,53-54
Journal	Journal of Infection
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/S0163-4453(90)92324-E
State	Published - Jan 1990
Externally published	Yes

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title = "Progressive multifocal leukoencephalopathy-remission with cytarabine",

abstract = "A 51-year-old women who was in complete remission from non-Hodgkin's lymphoma, developed a rapidly progressive dementia. Progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of a rising antibody titre to JC polyomavirus in cerebro-spinal fluid and serum and the presence of diffuse white matter changes on magnetic resonance imaging. She was treated initially with intravenous cytarabine and showed minimal improvement. Rapid improvement occurred when intrathecal cytarabine was added and the patient is in complete remission from both lymphoma and PML 20 months later.",

author = "T. O'Riordan and Daly, \{P. A.\} and M. Hutchinson and Shattock, \{A. G.\} and Gardner, \{S. D.\}",

year = "1990",

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AU - O'Riordan, T.

AU - Daly, P. A.

AU - Hutchinson, M.

AU - Shattock, A. G.

AU - Gardner, S. D.

PY - 1990/1

Y1 - 1990/1

N2 - A 51-year-old women who was in complete remission from non-Hodgkin's lymphoma, developed a rapidly progressive dementia. Progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of a rising antibody titre to JC polyomavirus in cerebro-spinal fluid and serum and the presence of diffuse white matter changes on magnetic resonance imaging. She was treated initially with intravenous cytarabine and showed minimal improvement. Rapid improvement occurred when intrathecal cytarabine was added and the patient is in complete remission from both lymphoma and PML 20 months later.

AB - A 51-year-old women who was in complete remission from non-Hodgkin's lymphoma, developed a rapidly progressive dementia. Progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of a rising antibody titre to JC polyomavirus in cerebro-spinal fluid and serum and the presence of diffuse white matter changes on magnetic resonance imaging. She was treated initially with intravenous cytarabine and showed minimal improvement. Rapid improvement occurred when intrathecal cytarabine was added and the patient is in complete remission from both lymphoma and PML 20 months later.

UR - https://www.scopus.com/pages/publications/0025162211

U2 - 10.1016/S0163-4453(90)92324-E

DO - 10.1016/S0163-4453(90)92324-E

M3 - Article

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VL - 20

SP - 51-52,IN1-IN3,53-54

JO - Journal of Infection

JF - Journal of Infection

IS - 1

ER -

Progressive multifocal leukoencephalopathy-remission with cytarabine

Abstract

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