Abstract
A 50-year-old woman, who survived 12 years following cranial irradiation for a frontal tumor, developed a delayed-onset, progressive neuropsychiatric disorder culminating in florid psychosis. Her symptoms and deficits fit the clinical pattern of a progressive subcortical disease and correlated with neuroimaging evidence of continuing white matter degeneration. We compare this irradiation-induced dementia to other toxic and degenerative dementias, and consider the role of cerebral white matter in the genesis of psychotic symptoms.
| Original language | English |
|---|---|
| Pages (from-to) | 125-129 |
| Number of pages | 5 |
| Journal | Neuropsychiatry, Neuropsychology and Behavioral Neurology |
| Volume | 7 |
| Issue number | 2 |
| State | Published - 1994 |
| Externally published | Yes |
Keywords
- Dementia
- Neuropsychological testing
- Radiotherapy