Progress in vaccine development for infectious diseases-a Keystone Symposia report

Jennifer Cable, Barney S. Graham, Richard A. Koup, Robert A. Seder, Katalin Karikó, Norbert Pardi, Dan H. Barouch, Bhawna Sharma, Susanne Rauch, Raffael Nachbagauer, Mattias N.E. Forsell, Michael Schotsaert, Ali H. Ellebedy, Karin Loré, Darrell J. Irvine, Emily Pilkington, Siri Tahtinen, Elizabeth A. Thompson, Yanis Feraoun, Neil P. KingKevin Saunders, Galit Alter, Syed M. Moin, Kwinten Sliepen, Gunilla B. Karlsson Hedestam, Hedda Wardemann, Bali Pulendran, Nicole A. Doria-Rose, Wan Ting He, Jennifer A. Juno, Sila Ataca, Adam K. Wheatley, Jason S. McLellan, Laura M. Walker, Julia Lederhofer, Lisa C. Lindesmith, Holger Wille, Peter J. Hotez, Linda Gail Bekker

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The COVID-19 pandemic has taught us many things, among the most important of which is that vaccines are one of the cornerstones of public health that help make modern longevity possible. While several different vaccines have been successful at stemming the morbidity and mortality associated with various infectious diseases, many pathogens/diseases remain recalcitrant to the development of effective vaccination. Recent advances in vaccine technology, immunology, structural biology, and other fields may yet yield insight that will address these diseases; they may also help improve societies' preparedness for future pandemics. On June 1-4, 2022, experts in vaccinology from academia, industry, and government convened for the Keystone symposium "Progress in Vaccine Development for Infectious Diseases" to discuss state-of-the-art technologies, recent advancements in understanding vaccine-mediated immunity, and new aspects of antigen design to aid vaccine effectiveness.

Original languageEnglish
Pages (from-to)65-86
Number of pages22
JournalAnnals of the New York Academy of Sciences
Issue number1
StatePublished - 1 Jun 2023


  • antigen design
  • mRNA vaccines
  • structural vaccinology
  • vaccine delivery
  • vaccine hesitancy
  • vaccines


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